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Bargonetti, Jill

One or more keywords matched the following items that are connected to Bargonetti, Jill

Item Type	Name
Grant	p53-Independent Cell Death Signaling by Mitomycin DNA Adducts
Academic Article	p53 binds to a constitutively nucleosome free region of the mdm2 gene.
Academic Article	DNA adducts of decarbamoyl mitomycin C efficiently kill cells without wild-type p53 resulting from proteasome-mediated degradation of checkpoint protein 1.
Academic Article	A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation.
Academic Article	A DNA damage signal is required for p53 to activate gadd45.
Academic Article	8-Amino-adenosine activates p53-independent cell death of metastatic breast cancers.
Academic Article	Dietary downregulation of mutant p53 levels via glucose restriction: mechanisms and implications for tumor therapy.
Academic Article	Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway.
Academic Article	Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells.
Academic Article	Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator.
Academic Article	Impedimetric detection of mutant p53 biomarker-driven metastatic breast cancers under hyposmotic pressure.
Academic Article	Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4.
Academic Article	Homozygous mdm2 SNP309 cancer cells with compromised transcriptional elongation at p53 target genes are sensitive to induction of p53-independent cell death.
Academic Article	Hot Spot Mutation in TP53 (R248Q) Causes Oncogenic Gain-of-Function Phenotypes in a Breast Cancer Cell Line Derived from an African American patient.
Academic Article	Estrogen-activated MDM2 disrupts mammary tissue architecture through a p53-independent pathway.
Academic Article	p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis.
Academic Article	Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells.
Academic Article	The p53 protein is an unusually shaped tetramer that binds directly to DNA.
Academic Article	In vivo footprinting and DNA affinity chromatography for analysis of p53 DNA binding ability.
Academic Article	Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element.
Academic Article	Mutant p53 forms a complex with Sp1 on HIV-LTR DNA.
Academic Article	Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta.
Academic Article	A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells.
Academic Article	Functional consequences of the interactions of the p53 tumor suppressor protein and SV40 large tumor antigen.
Academic Article	A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.
Academic Article	Mouse double minute 2 associates with chromatin in the presence of p53 and is released to facilitate activation of transcription.
Academic Article	Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D.
Academic Article	Mitomycin-DNA adducts induce p53-dependent and p53-independent cell death pathways.
Academic Article	Disruption of the p53-Mdm2 complex by Nutlin-3 reveals different cancer cell phenotypes.
Academic Article	p53 represses Sp1 DNA binding and HIV-LTR directed transcription.
Academic Article	Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry.
Concept	Cell Line
Concept	Cell Line, Tumor
Academic Article	Targeting Triple Negative Breast Cancer with a Nucleus-Directed p53 Tetramerization Domain Peptide.
Academic Article	PARP-Targeted Auger Therapy in p53 Mutant Colon Cancer Xenograft Mouse Models.
Academic Article	Patient-derived tumor organoids with p53 mutations, and not wild-type p53, are sensitive to synergistic combination PARP inhibitor treatment.

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